Nuclear factor erythroid 2-related factor 2
Web14 apr. 2024 · HIGHLIGHTS. who: Yusuke Kubo from the Department of Anatomy and Cell Biology, Uniklinik RWTH Aachen, Wendlingweg, Aachen, Germany have published the … WebNuclear factor erythroid 2-related factor 2 Gene Nfe2l2 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 597 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History Download Entry feedback Function
Nuclear factor erythroid 2-related factor 2
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Web1 feb. 2024 · Nuclear factor-erythroid 2 related factor 2 (Nrf2) is a ubiquitous master transcription factor that upregulates antioxidant response elements (AREs) … WebNuclear factor erythroid 2-related factor 2 is a positive regulator of human bile salt export pump expression. Nrf2 is a positive transcriptional regulator of human BSEP expression. …
Web10 jun. 2016 · Nuclear Factor Erythroid-2 Related Factor 1 cap ‘n’ collar basic leucine zipper musculoaponeurotic fibrosarcoma oncogene ARE antioxidant response element EpRE electrophile responsive element C/EBP-β CCAAT Enhancer-binding protein ROS reactive oxygen species NQO1 NAD (P)H: quinone oxioreductase 1 GSH GST … Web1 aug. 2024 · Abstract. Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) is a transcription factor that can regulate downstream target gene expression. Kelch-like …
WebExpression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in healthy and pathologic placentas of human and rat Nuclear factor erythroid 2-related factor 2 (NRF2), also known as nuclear factor erythroid-derived 2-like 2, is a transcription factor that in humans is encoded by the NFE2L2 gene. NRF2 is a basic leucine zipper (bZIP) protein that may regulate the expression of antioxidant proteins that protect against … Meer weergeven NRF2 is a basic leucine zipper (bZip) transcription factor with a Cap “n” Collar (CNC) structure. NRF2 possesses seven highly conserved domains called NRF2-ECH homology (Neh) domains. The Neh1 domain is a … Meer weergeven Activation of NRF2 induces the transcription of genes encoding cytoprotective proteins. These include: • NAD(P)H … Meer weergeven Dimethyl fumarate, marketed as Tecfidera by Biogen Idec, was approved by the Food and Drug Administration in March 2013 following the … Meer weergeven NFE2L2 has been shown to interact with MAFF, MAFG, MAFK, C-jun, CREBBP, EIF2AK3, KEAP1, and UBC. Meer weergeven NFE2L2 and other genes, such as NFE2, NFE2L1 and NFE2L3, encode basic leucine zipper (bZIP) transcription factors. They share highly … Meer weergeven NRF2 is ubiquitously expressed with the highest concentrations (in descending order) in the kidney, muscle, lung, heart, liver, and brain. Meer weergeven Genetic activation of NRF2 may promote the development of de novo cancerous tumors as well as the development of atherosclerosis by raising plasma cholesterol … Meer weergeven
Web21 feb. 2024 · However, its potential role in septic cardiomyopathy remains undefined. STK3-mediated phosphorylation of Kelch-like ECH-associated protein 1 (KEAP1) was shown to suppress antioxidant gene transcription controlled by nuclear factor erythroid 2-related factor 2 (Nrf2) in macrophages.
Web26 nov. 2024 · Nuclear factor erythroid-related factor 2 (Nrf2) is a transcription factor that has a key role in controlling the intracellular redox environment by regulating the … omnifun gaithersburgWeb11 apr. 2024 · Curcumin exerts anti-inflammatory and anti-cancer effects by inhibiting NF-κB, signal transducer and activator of transcription-3 (STAT-3), nuclear factor erythroid 2-related factor 2 (NRF-2),... omni ft worth convention centerWeb11 apr. 2024 · Furthermore, the downregulation of nuclear factor erythroid 2-related factor 2 (Nrf2) and activation of toll-like receptor 4/nuclear factor-κB signaling were observed in POCD rats, which were greatly rescued by miR-190a-3p. Lastly, the Nrf2 luciferase activity and Nrf2 levels in HT22 cells were extremely improved by miR-190a-3p. omnify employee benefit solutionsWebPurpose of review: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates a wider range of downstream pathways than previously thought. … omni furniture gallery plano txWeb21 mrt. 2024 · NFE2 (Nuclear Factor, Erythroid 2) is a Protein Coding gene. Diseases associated with NFE2 include Erythroleukemia and Polycythemia . Among its related pathways are Gene expression (Transcription) and RNA Polymerase I Promoter Opening . omni fulton market chicagoWebAutophagy, an evolutionarily conserved catabolic process, is the most important pathogenic events in the development and progression of liver diseases. Deregulation of Nrf2 is … omnigatherumWeb10 apr. 2024 · Nuclear factor erythroid 2-related factor 2 in human papillomavirus-related cancers. Macrophage nuclear factor erythroid 2-related factor 2 deficiency promotes innate immune activation by tissue inhibitor of metalloproteinase 3-mediated RhoA/ROCK pathway in the ischemic liver. omnify health savings account