WebFirst-generation antihistamines block both histaminic and muscarinic receptors as well as passing the blood-brain barrier. Second-generation antihistamines mainly block histaminic receptors but do not or only minimally cross the blood-brain barrier. WebSep 1, 2005 · Second-generation OTC antihistamines These are newer medicines. Many treat allergy symptoms without causing sleepiness. Common kinds include: Loratadine (two brand names: Alavert, Claritin) Cetirizine (one brand name: Zyrtec) Fexofenadine (one brand name: Allegra) Note: Some antihistamines are mixed with other medicines.
Antihistamines: Definition, Types & Side Effects
WebAntihistamines that target the histamine H 1 -receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing). In addition, they may be used to … WebAllergy & Cold: Dosing, Uses, Side Effects, Interactions, Patient Handouts, Pricing and more from Medscape Reference asml gsa standards
First-Generation and Second-Generation of Antihistamines: …
WebOct 12, 2024 · Antihistamines are a group of medicines which act to block the effects of the chemical called histamine in the body. Either H1 or H2 histamine receptors can be blocked by medicines, but the group commonly known as antihistamines blocks the H1 receptor. They have a number of uses, but are most often used to treat allergies. Second-generation H1-antihistamines are newer drugs that are much more selective for peripheral H1 receptors as opposed to the central nervous system H1 receptors and cholinergic receptors. This selectivity significantly reduces the occurrence of adverse drug reactions, such as sedation, while still providing effective relief of allergic conditions. The reason for their peripheral selectivity is that most of these compounds are zwitterionic at physiological pH (around pH 7.4). … WebMar 2, 2024 · Histamine is a biologically active substance that potentiates the inflammatory and immune responses of the body, regulates physiological function in the gut, and acts … asml beta